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U-47700 is an opioid analgesic drug developed by a team at Upjohn, that acts as a selective agonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphine in animal models. In addition, order u47700 online now.
U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered it was the most active.
U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.
Uses of U47700
U47700 like other opioids does produce a number of undesirable after effects that are colloquially known as the “crash”. These include agitation, irritability, negative emotional states, cognitive fatigue, difficulty thinking, anxiety, depression and lack of motivation.
U47700 has a marked toxicity relative to dose due to its extreme potency in comparison to traditional opioids and opiates. This makes it a less than ideal recreational compound with significant risk of harm to the user. So you can order the powder online and have it delivered with not problems.